Increased Muscle Pumps, Energy And Recovery! 1-NO is an exciting new generation approach to amino acid based nitric oxide promotion. 1-NO combines AKG with ornithine a-ketoglutarate (OKG) to promote NO production through two pathways. The addition of OKG augments the NO stimulatory action of AKG by providing a secondary route to plasma arginine elevation. OKG goes beyond AKG however as it also raises plasma levels of plasma glutamine, polyamines, growth hormone and insulin.